as of now, i didn't seen such cases. but when do transport for data source which was running delta loads in prod, we need take care the delta records from queues.
i.e we need to clear all the queues(SMQ1/SM13/LBWQ/RSA7) by loading data into bw.
once all queues are 0 records then we can transport new changes to prod. other wise there would be chance to miss delta records.
in this case better to lock system to stop transactions.